In-circling and in-sphering and AI for used in designing the layout for well spaced out stacked circuits along with better use of curved wiring and communications bridging.
Using optical power and optical comms to power circuit tiny cities on Thermo optic pins which also partially manage thermo issues with light.
3 cycle high frequency processors. null cycles, compute cycles and static discharge dump cycles running virtual 5GHz and beyond and a real clock close to 50GHz and beyond. good for power management in 3D.
Evolutionary Synaptic Cellular Automata used to to find optimal logic configuration.
Converting Sat problems into omni-symmetric problems like sudoku and using in-circling and reducing the grid into two congruent grids where both grids combined is equal to the data in the original grid in order to better optimise for learning from falsified solutions and learning reductions that can be implied.