Actually, i believe its possible. Of course , sometimes, what others people say will effect on us, maybe us feel a lit doubt, but nothing strong enough to touch our self-esteem. But i really believe on limits, that isnt good be reallt no caring about nothing and no one opinion, because its good we be opened to listen people' s opinions, by it we can improve ourself. But give so much attention to that, enough to make us feel down, its resally bad.
So i think everything is about balance