Medication question

Hi everyone, I have been using Zoloft (actually generic equivalent) for about a decade now. Started with 25 mg. Now I am taking 150 mg. It has not completely stopped working, but due to my husband's mental illness - which you can find in my other posts - I seem to find myself depressed and crying a lot. What meds have you tried for depression? What side effects did you have? What was you experience. Thanks.

I started Sertraline about a year ago to quiet the music in my head, stop the ruminating and help me sleep better. I am currently on 75 mg. It takes the edge off and I could go to 150 mg if I asked the doctor.
I was on anti-depressant/anti-anxiety meds about 28 years ago. This was the old-school Imipramine and Buspar. These proven meds had been around a long time and were in mild doses.
I had housemates that were on Prozac. There are so many choices out there now, that it makes Prozac look old.
Really the older meds still help some people that can't tolerate certain classes of drugs. ECT helps those that can't tolerate any meds. Nothing wrong with that.
You have to differentiate how much of the depression is 'situational' and how much is biological.
My only side effect really was dry-mouth. My body did adjust after a year or so and I always had my ice water with me. It got better.
Best of luck to you.

Thank you. It's hard to differentiate situation induced from biological after 17 years of "situation." But I understand what you are saying. Thanks again for your reply.