Why do you care about "normal"?
Yes most people don't get that the human race is basically filled with pricks, idiots (insert other insults). Notice though that second word- with the advent of the internet our ability to find people who are average, who get it has increased.
You said that you've tried therapy and medications and they haven't worked- I wonder if perhaps you might have a different disorder besides depression and the reason therapy/medications haven't worked is because your doctors were not addressing part of the problem.
I understand how you feel. I don't hang out with people, I think/feel that people are stupid, stubborn pricks for the most part. Though I have come to realize that some people are very good people, nice, friendly, and intelligent on some subjects, yet I still can barely stand hanging out.
Chondro mention ECT- I have treatment resistant depression and tried ECT, it helped me. The treatment isn't necessarily to treat who you are/your personality but to make it so you get content with those things.