Wow - That is really suprising to me about the weight gain with Seroquel. I have been on it for almost 6 years, have lost over 100 pounds and Serouquel is being studied as a weight loss drug!
My Pdoc recomended it to me years ago while we were switching around the cocktail of pills I take and he asked me if there were any other concerns and I said I was tired of being fat. So, he told me about his findings with Seroquel.
It took a while to work, but with various combinations over the years I have managed to pull off 100 pounds without any diet or exersise other than having a small amout of anorexia now and hten and I am a big gal so I can afford some of that! HA!
My Pdoc has told me he has had to pull some of his patients off of Seroquel after a year or so because they simply lost too much weight and were at a border line of where he should take them off of them.
We all know pills can react differently with other people, but I would check with your doctor again about your weight gain problems with this.
Hope you find an answer.