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Has anyone found 25mg of lamictal to be therapeutic? Higher

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Has anyone found 25mg of lamictal to be therapeutic? Higher

Postby penelopercival » Tue Mar 20, 2018 5:01 am

*Trigger Warning*

Hi all! I started on 25mg of lamictal after years of failed antidepressants and finally being officially diagnosed with bp2. I did the usual titration of 25mg for two weeks, 50mg for two, then up to 75mg. At 25mg I noticed a difference pretty aimmediately but assumed it was a placebo effect from finally getting the right help. At 50mg I felt even better but had an incredibly scary manic episode one night after only a few drinks; disembodied laughing, panic attacks, cold harsh words, grief, all in minute long cycles. I chalked this up to the fact that I clearly cannot drink a drop on these meds. But then the nightmares started. Anxiety has always been very debilitating for me, and I was having vivid anxious scenario type dreams every night that lasted throughout my days. I then went up to 75mg and a few days later what had happened to me that one night at 50mg started and lasted for five days straight. The grief was immense. It was like a barrier had been unlocked after years, but it wasn't just that; memories came back, which would have been something to work through, if not for the ten minute cycling from this to rage to suicidal threats to disembodied laughing to weird philosophical rants. I immediately lowered myself (safely) back down to 25mg and was planning to go off entirely, but I've stayed there for almost a month now. It seems to be turning my life around. I feel like I had somewhat of a breakthrough that would have taken years of therapy to reach during that week of absolute hell, but could not stay doing that. So I guess my questions are:

1) Does anyone find 25mg helpful? Or am I just riding a breakthrough wave and will crash again?
2) Was this week of hell showing me that the dose was working or too high? Should I have tried to stick it out? (I almost called 911 multiple times so probably not.)
3) Has anyone else experienced this effect? The unpacking of grief? Could it have been more my feelings and memories coming back than it was a manic reaction to the medication?
4) Has anyone had a bad reaction going up, went down for a bit, and then tried again?

Sorry for the loooong story I'm lost :(
Last edited by quietgirl2538 on Tue Mar 20, 2018 2:30 pm, edited 1 time in total.
Reason: added a trigger warning; no other changes
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Re: Has anyone found 25mg of lamictal to be therapeutic? Higher

Postby z7z » Tue Mar 20, 2018 7:46 pm

I usually give a medicine a good chance before giving up on it as the side effects usually go away. When I started Lithium I had dry mouth and my thyroid was low, but I took a thyroid medication and the dry mouth went away. I have been fairly stable on it and can have a few drinks. It sounds like anxiety is a big symptom of yours and although not for everyone, benzos can help you to relax and they are healthier than drinking alcohol according to my doctor. Just a guess, but I don't think that dosage will keep you stable. I'd ask your pdoc.
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Re: Has anyone found 25mg of lamictal to be therapeutic? Higher

Postby Jellybeanery » Tue Mar 20, 2018 11:14 pm

Well, for me, no. 25 mg is too little. It is the "starting dose". I believe 200 mg is the "therapeutic dose". I am on 400 mg though. I don't think Lamictal can trigger hypomania/mania, but it does not prevent it from happening. Lamictal is geared more towards the treatment of depression.

It sounds to me like this is just not the right medication for you. I suggest talking to your pdoc about it.
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Re: Has anyone found 25mg of lamictal to be therapeutic? Higher

Postby potemkin » Wed Mar 21, 2018 8:28 pm

I don't think it is a therapeutic dose. This might be a placebo effect. The therapeutic dose starts at 100 mg.
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Re: Has anyone found 25mg of lamictal to be therapeutic? Higher

Postby voracious_lemon » Thu Mar 22, 2018 11:13 am

I personally didn't even find 300mg therapeutic, but that's just me. I also think 25mg is too low to really do anything.
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