by Klrskies » Tue Jun 25, 2024 10:51 pm
I posted on this topic in 2015 and want to update what i've experienced in 9 years.
After several decades of degrading mental and physical health, I became sick enough to first be DX'd with Clonal Mast cell activation after a bone marrow biopsy. But the normal treatments for nast cell didn't resolve all my issues. I always had sleep issues... sleeping a few hours then waking up around midnight and not able to return to sleep near dawn. Specialists could not resolve it and gave me sleeping pills, muscle relaxers, tricyclics, benzos, prednisone and I tried supplements with varying degrees of success.
In 2022 I began having tremors, ocular clonus, anxiety, trouble walking, difficulty finding my words and Insomnia. I saw many doctors and specialists but really didn't get a DX. I learned that my symptoms were caused by serotonin toxicity. I stopped all med and supplements that elevated serotonin. My doctor prescribed cyproheptadine, a serotonin antagonist which I couldn't take when my symptoms were at their worst but can take 6 months later. It's pretty common for patients to not tolerate many meds, supplements, vitamins and high tryptophan (Amino acid and serotonins precursor) foods, bright sunlight, emotional stress, often becoming quite calm seeking and introverted.
Conventional medicine says that Serotonin Toxicity or Serotonin Syndrome as it's frequently called, ends within 72 hours of stopping all serotonin elevating drugs and supplements but for many that's not the case for many. Sensitivity to serotonin elevating drugs, supplements and stimuli will bring symptoms and need to be aware of these for months after initial serotonin syndrome and some degree of sensitivity permanently.
I've begun genetic testing to search for abnormalities within the neurotransmitter's systems.