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'Serotonin can increase anxiety, not decrease it' - a study

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Re: 'Serotonin can increase anxiety, not decrease it' - a study

Postby NimplyDinply » Mon Jun 22, 2015 5:48 pm

clearskies84 wrote:
NimplyDinply wrote:
snookiebookie wrote:I'm on pregabalin now. That helps with the anxiety symptoms...doesn't stop the anxiety though. It also helps me sleep.


I'm also on Lyrica, 75 mg a night and it helps me to sleep but I still have a bit of anxiety during the day. Like you, I've been on a lot of antidepressants. The only thing that really helped was
Effexor 10 years ago for a lot of panic attacks I was having.

Maybe some form of therapy and/or natural remedies are the only things that can help at this stage?

"natural remedies" are nonsense.


I'm not talking naturopathy here. Some people may have very low magnesium, which can actually cause anxiety. Or they don't get much omega three, or they are b6/b12 deficient. There are many deficiencies that can create anxiety symptoms that I cannot honestly say that supplementation will not help. It hasn't for me, but for others it might.
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Re: 'Serotonin can increase anxiety, not decrease it' - a study

Postby clearskies84 » Tue Jun 23, 2015 1:50 am

NimplyDinply wrote:I'm not talking naturopathy here. Some people may have very low magnesium, which can actually cause anxiety. Or they don't get much omega three, or they are b6/b12 deficient. There are many deficiencies that can create anxiety symptoms that I cannot honestly say that supplementation will not help. It hasn't for me, but for others it might.

I recently heard alot of that vitamin stuff is bunk, and doctors prescribe this stuff due to companies wanting publicity, there's been some research on vitamin supplements, I don't believe the outcome was positive. You can probably find more with a few google trips, I'm too lazy right now, lol.
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Re: 'Serotonin can increase anxiety, not decrease it' - a study

Postby creative_nothing » Tue Jun 23, 2015 10:47 am

What is the relation between hypomania and anxiety?
Can hypomania induce or be a kind of anxiety?
Can it be diagnosed as anxiety?
I guess hypomania is marked by high levels of serotonin.
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Re: 'Serotonin can increase anxiety, not decrease it' - a study

Postby NimplyDinply » Tue Jun 23, 2015 12:58 pm

There is a hypomania marked by agitation and irritability. These are known symptoms of anxiety. I think one difference is, when you're hypo/manic, you don't need as much sleep. That's not the case with anxiety.
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Re: 'Serotonin can increase anxiety, not decrease it' - a study

Postby creative_nothing » Tue Jun 23, 2015 2:51 pm

Well, I do sleep well. Althought at times, my head is so fast that it prevents me from sleeping. Usually I can slow it down in a hour or two.

I thought however that people with GAD had major troubles with getting sleepy.

And I wonder how do they split those who have troubles sleeping(GAD) from those who do not need to sleep(Hypomania) if that exists.
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Re: 'Serotonin can increase anxiety, not decrease it' - a study

Postby NimplyDinply » Tue Jun 23, 2015 4:53 pm

I've experienced both, so I'll tell you how it is for me. With GAD, I worry excessively either before going to sleep or in the middle of the night, and my worries make it hard to go to sleep. So I get 4 hours and feel like shite the next day. Then there are other times when I'm irritable, agitated, mind racing and get 4 hours of sleep and it feels like I got 8. I don't feel particularly sleepy.

I usually need 7-8 to feel refreshed.

Hope this helps
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Re: 'Serotonin can increase anxiety, not decrease it' - a study

Postby Rigning » Thu Jul 02, 2015 4:34 am

would explain why cipralex made me paranoid and zoloft made me choke and snri tried to kill me by tensing my muscles 24/7. these drugs are crazy if you ask me. and we're not allowed to smoke pot because turning into a social menace on alcohol is so much better. tsh.
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Re: 'Serotonin can increase anxiety, not decrease it' - a study

Postby Klrskies » Tue Jun 25, 2024 10:51 pm

I posted on this topic in 2015 and want to update what i've experienced in 9 years.

After several decades of degrading mental and physical health, I became sick enough to first be DX'd with Clonal Mast cell activation after a bone marrow biopsy. But the normal treatments for nast cell didn't resolve all my issues. I always had sleep issues... sleeping a few hours then waking up around midnight and not able to return to sleep near dawn. Specialists could not resolve it and gave me sleeping pills, muscle relaxers, tricyclics, benzos, prednisone and I tried supplements with varying degrees of success.

In 2022 I began having tremors, ocular clonus, anxiety, trouble walking, difficulty finding my words and Insomnia. I saw many doctors and specialists but really didn't get a DX. I learned that my symptoms were caused by serotonin toxicity. I stopped all med and supplements that elevated serotonin. My doctor prescribed cyproheptadine, a serotonin antagonist which I couldn't take when my symptoms were at their worst but can take 6 months later. It's pretty common for patients to not tolerate many meds, supplements, vitamins and high tryptophan (Amino acid and serotonins precursor) foods, bright sunlight, emotional stress, often becoming quite calm seeking and introverted.

Conventional medicine says that Serotonin Toxicity or Serotonin Syndrome as it's frequently called, ends within 72 hours of stopping all serotonin elevating drugs and supplements but for many that's not the case for many. Sensitivity to serotonin elevating drugs, supplements and stimuli will bring symptoms and need to be aware of these for months after initial serotonin syndrome and some degree of sensitivity permanently.

I've begun genetic testing to search for abnormalities within the neurotransmitter's systems.
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