Angles, that's how I took twistermind's words also, but hey, what do I know, perhaps there is some story here where twistermind sicked her dog on inverse's favorite kitten, I don't really know either and can't speak for their character with any authority.
Abstractly speaking though
If you expect honest and open communication
I wouldn't. That's not what civilization is built on. Certainly you shouldn't trust words too much - not even your own.
Twistedmind has a fake persona that she uses to control people
Well, I am impressed. I wouldn't think she has it in her. Controlling people is not easy, no matter how much one wants and tries. have been trying to control my boss into giving me a raise and a leave in autumn instead of summer and nada.... With these abilities twistermind could be a president.
the second despicable.
I don't think it's despicable, I think it's entirely natural. What's despicable is manipulating people into something that will cause them harm and hurt them, but it's the problem with intent, not manipulation itself. If a person wants to be liked (and that's most people. And if they don't want to be liked, they will play other game like "I am so much better than you and you'll know it". I usually play the game of "I don't wanna fight and let's just relax and leave me alone" - though not always, mind, as you might have noticed), so most people do very much consider how they words they say and things will do will affect other people's feelings towards them. Of course they do! "will it make them like me, will it make them respect me, will they hate me for it, will it lead to conflict".
and when they don't, it's when they blab something without realizing the consequences, because they are socially unintelligent. Nobody appreciates that in my experience. E.g., you can be even critical and all that, but you still have to consider how it sounds and whether a person gets any positives from you also.
If someone is that sincere as to just say whatever without considering how it will affect opinion of others on them, they are either an angel, or they'll be likely out of job and out of friends....