https://www.msdmanuals.com/professional ... a#v1087755Exchange Transfusion
This treatment can rapidly remove bilirubin from circulation and is indicated for severe hyperbilirubinemia, which most often occurs with immune-mediated hemolysis.
https://en.wikipedia.org/wiki/Autoimmun ... tic_anemiaThe causes of AIHA are poorly understood. The disease may be primary, or secondary to another underlying illness. The primary illness is idiopathic (the two terms used synonymously). Idiopathic AIHA accounts for approximately 50% of cases.[9] Secondary AIHA can result from many other illnesses. Warm and cold type AIHA each have their own more common secondary causes. The most common causes of secondary warm-type AIHA include lymphoproliferative disorders (e.g., chronic lymphocytic leukemia, lymphoma) and other autoimmune disorders (e.g., systemic lupus erythematosus, rheumatoid arthritis, scleroderma, crohn's disease, ulcerative colitis). Less common causes of warm-type AIHA include neoplasms other than lymphoid, and infection. Secondary cold type AIHA is also caused primarily by lymphoproliferative disorders, but is also commonly caused by infection, especially by mycoplasma, viral pneumonia, infectious mononucleosis, and other respiratory infections. Less commonly, it can be caused by concomitant autoimmune disorders.[10]
Does this mean that severe hyperbilirubinemia in neonatals can be caused by an underlying autoimmune condition? It said somewhere in there that for premies, the risk from bilirubin poisoning increases with weeks born premature, and that for under 35 week gestation, no amount of bilirubin is considered safe. Apparently, it messes with the neural network. -- Wed Jul 25, 2018 1:13 pm --
seabreezeblue wrote:Interesting.. no idea if i had jaundice (i'll ask my mother), but my daughter did.
I'll have to take a look into that.
Were you or your daughter born premature? It sounds like it's riskier for premies, esp. born before 35 weeks gestation (more than 5 weeks premature).