V0iD wrote:Hi guys! I don't have ADHD, but for other reasons I'm taking dopamine blockers and it severly reduces my energy (hyperactivity) and sensitivity to pleasure (impulsivity). Anyone who has ADHD ever tried dopamine blockers?
It would probably fix most of the problems.
person A does not have disorder B.
person A has side effect C while taking drug D.
therefore person with disorder B should take drug D.
the problem with the hypothesis is that the person with disorder B has a neurological defect that results in drug D not having the same effect in this person as the person without the defect.
that said, have you contacted shire pharmaceuticals (patent holders of ritalin)? they might be interested in your research.
the standard 'treatment' for ADHD is amphetamines (ritalin/adderall) and these are dopamine reuptake inhibitors, and they have the effect of stimulating the dopamine pathway, which presumably is naturally low in these individuals. for this reason, a dopamine blocker would be anticipated to make the symptoms WORSE in these individuals, not better.
however, thanks for the suggestion, and i hope there is some large pharm company that pursues your line of inquiry, that this debate might be settled and these patients helped!