by Jemini » Thu Aug 16, 2007 5:28 pm
Having had a few manic episodes with psychotic features, all of which were during withdrawal from long-term use of serotonergic anti-depressants, and also like yourself having used and abused pot and alcohol (and LSD when I was younger), and finally, having studied psychology and the brain since before the Prozac revolution and followed as much of the research as I can, I have to say, the answer to your question is: good question.
There are certainly fixed views out there, and bipolar is all the rage these days among psychiatrists, who keep inventing new flavors to accommodate the patients they see who don't perfectly match the existing descriptions. Then there are studies showing brain scans of bipolar patients that show abnormalities in the frontal cortex, in the amygdala, etc, etc. However these studies have some critical flaws, some of which I've seen critiqued (and largely ignored) by other researchers, some of which I've yet to encounter but which seem obvious:
1. Studies showing brain structure abnormalities fail to control for other bipolar patients not given medications over the length of time it takes for structural changes to be observable. I.e. they fail to conclusively show that such brain abnormalities are not the result of medications.
2. The studies are on "bipolar patients". In other words, the studies divide people according to non-scientific, subjective labels given the subjects by psychiatrists. So what? Well, for one thing, these labels may be very likely to be given to anyone who has those brain abnormalities, and in that sense, those abnormalities may be responsible for the observed or reported behaviors, but then, saying that there is some separate, tangible reality that is bipolar, which both caused the diagnosis and caused the brain abnormalities is unsupported. Cause and effect are problem areas for psychiatric doctrine. These same results could indicate brain abnormalities arising from diverse causes, including but not limited to drug abuse or the prolonged use of some medications, which in turn give rise to mood cycling, depression, and psychosis, for any number of reasons.
Having said all that, it *is* known that many medications can induce mania and psychosis in a small percentage of people. To say that this is "revealing" previously unobserved bipolar is stretching credulity for me, given that there exists no way to demonstrate the existence of bipolar other than interpretation of reported or observed behavior. If there were a genetic test, and those people whose first manias arose from taking medications were then tested and found positive for the gene, this assertion would make sense.
Instead, the basis of the assertion, as far as I can tell, has to do with a few factors. 1) Doctors like to pathologize and sell treatment. 2) Plenty of data does show that each successive depressive manic episode correlates to an increased likelihood of future episodes, so doctors are wanting to err on what they perceive to be the side of caution (not remotely believing their treatments themselves might be part of the problem). And 3) psychiatry has fallen in love with the biochemical model that justifies medication as primary treatment and finally solidifies the idea that psychiatry is actual, medical science. Therefore, bipolar is real, it is a medical condition, and it is innate to an individual. Medications are treatment, theoretically cure, definitely not cause. And drugs, which of course are totally different from medications because they weren't created by Science, may mimic this medical condition, but could no more cause it than medications (since, after all, drugs are drugs are drugs).
There is A LOT of evidence that marijuana and hallucinogens aggravate and can initiate kindling, and thereby can cause or aggravate mania and psychosis. If you comprehend the idea that bipolar is NOT an established medical condition with an established etiology, but rather is NOTHING MORE than a syndrome of observable behaviors for which some treatments have been shown effective, than you may come to the conclusion, as I have, that mania and psychosis induced by drug abuse is still bipolar. And that before seeking extensive intrusive treatment for this, you are very wise to stop using drugs and alcohol, working as needed on the emotional issues that drive you to these in the first place.
The DSM says (of most disorders) that the patient must meet such and such criteria which cannot otherwise be explained by another diagnosis or by drug use. This clever legalese-like maneuvering implies that there is some underlying medical reality, which must not be mistaken for another similar-looking syndrome, while simultaneously providing a lot of leeway for the completely subjective and biased way in which psychiatrists actually choose a diagnosis. However it contains one bit of real wisdom, which is that if the condition *is* being caused by active drug use, or some other identifiable factor, you need to eliminate that factor as a first step.
And, coming full circle, one of the things I eventually figured out from my research and quite painful, damaging experiences, was not only to eliminate pot, but to eliminate the serotonergic drugs which have ALSO been linked to mania and psychosis, but for which EVEN LESS scientific research has been done as to why or how.
Being as jaded as I am, I also avoid psych meds as much as possible, with mixed results -- I still tend towards dysthymia and anxiety. But so far, no mania. I even feel less agitated in general, less likely to slip into insomnia, then when I was medicated. YMMV.[/i]