Need help, I think I have Tardive/hypersensitivity psychosis

I was injected with zyprexa for 6 months.

I have awoken in a hell since then, that I can not describe.

Every waking moment is literal unbearable.

I recently found the term Supersensitivity psychosis which seems to describe well what I have gone through and what I have now:

Here is the wikipedia definition:

"Tardive psychosis is a form of psychosis distinct from schizophrenia and induced by the use of current (dopaminergic) antipsychotics by the depletion of dopamine and related to the known side effect caused by their long-term use, tardive dyskinesia."

Help? I cannot take more of these olanzapine, they put me in this hell I will never find my way out.

Should I try more antipsychotics that caused this condition and which I've also read is intractable to more antipsychotics and may possibly only worsen my baseline state if I can't bear them and go off them and am even more insane?

Has anyone got this condition and if so what did help? Thanks for help.

It's abated slightly since I wrote the last post.

But I am still noxious, and I read in wikipedia that ondansetron can be one med that can help a bit. So I will see if I can get it, also I'll try acquire rhadiola, which wikip suggests can be good for repletion of dopamine.

If anyone knows about this diagnosis and can share how they percieve the world through it?

A day in my life is being bed ridden and basically hoping not to become noxious to the point of suicidality.

U should report the side effects to a civil rights organization such as CCHR.

My friend had tardive psychosis, everytime he tried to stop using medication, his psychosis came back in varying degrees, the antispcyhotics cause this sometimes. Its simiar to withdrawal in this way, in fact u may want to taper down slowly from your medication, find a dr. who is critical of psychiatric medication, as they can be very harmful and get him/her to lower u off it slowly. Are u in the US? There are many peer /survivor places u can go to get help with this im sure. U may need to just take it easy for 6 months following the end of taking the zyprexa, u may get some sypmtoms and try to talk about these with safe ppl, like peer advocates etc. Mabye u could try some acupuncture, relaxing things, mindfulness etc to help, the symtpms *should* disappear eveuntually. Im sorry your going thru this it makes me very angry, this is an unacceptable 'side' affect of anti psychotics.

Zyprexa withdrawal gave me psychosis I never had before taking it, it was HELL.

I got off Zyprexa by going on the benzo anxiety meds to deal with the panic attacks and anxiety from hell the zyprexa withdrawal was causing me. I was sick for months vomiting out my back door onto the steps when the waves of nausea would hit, the vomiting did give me some relief from the anxiety in a way. I don't know if taking Xanax , Clonopin and Ativan was the best way to get off zyprexa but that's what I did. Stupid doctors got all concerned because benzo anxiety meds are "addictive" due to the pleasant effects and produce bad withdrawals themselves but those withdrawals were nothing compared the ones from the "non addictive" motivation and pleasure robbing Zyprexa. Zyprexa was like an insidious thief in rob all pleasure from life department.

Olanzapine is structurally similar to clozapine, but is classified as a thienobenzodiazepine. That word "benzo" in the name must be why it causes panic attacks and insomnia during withdrawal and I guess the nausea and vomiting are the rebound effect of the extra hunger Zyprexa induces in its victims.

The criminals in Eli Lilly and Company have known that their product Zyprexa kills and sickens people since at least 1998.

This was revealed in a series of New York Times articles late December 2006. New York Times referred to internal memos and documents who clearly show that Eli Lilly and Company knew about the extreme dangers of their product Zyprexa, and intentionally lied to health personel and the public in order to profit from their customers death and suffering.

That's here http://zyprexakills.ath.cx/ maybe print this and show the clueless doctors, I also advise people to print out everything they can find on Zyprexa withdrawal , show it to the doctors and demand help and demand a medical explanation for the nausea and vomiting. I always hope someone will come back and post the medical explanation .

It's your choice. It is important not to stop taking medication before you are ready but you have the right to decide to terminate any given treatment. Since the mental health system got you started on medications, it also has a responsibility to help you terminate that treatment as safely as possible if that is your choice.

I hope you keep posting here, the criminals in Eli Lilly and Company offer no information on how to get off there toxic product Zyprexa so its up to victims to tell there stories and get the information out to others.

Yeah it should be said I have been off Zyprexa for 8 months and still I am noxious constantly.

I feel bodily unwell, and noxious maybe is the closest description.

Just took the first pill of Rhodiola Rosea and not sure if it helps yet or not.

I really think I need Ondansetron aswell.

I think what happened was, brain being flushed with APs to the point where dopamine reward system just crashed.

I could feel this happen 10 months ago, it was like the body being polluted from the inside at one of the, maybe the 7th injection with Zyprexa.

I think it's permanent this state, it's been 8 months off meds, and I think I was simply medicated until some essential loop of dopamine regeneration in the brain snapped like a twig, and I'm stuck with a brain that lacks one of the basic neurotransmitters: it makes the rest of the metabolites not work to much use cognitively and instead I'm stuck with like internal brain poisoning syndrome, that is the rest of the metabolites are not regulated in a physiological way and without a basic NT your brain just says, this is not a metabolical state I recognize, I feel noxious.

Like being fed poison to the brain to the point where you permantenly remove something and you are now permanently noxious wether you take the causing agent anymore or not, which I haven't for 8-9 months.

Oh and anhedonia aswell. I'm a smoker and progressively over being injected the normal positive experience from ciggarettes that smokers have, just became nothing and instead I feel noxious from smoking them aswell, just tastes like some cleaning substance like most anything I eat too.

It's tough to just spend your time doing anything, granted I can't study anymore, and I accept it, but it's rough getting time to pass by when you are noxious/ have anhedonia / and also feel a LOT cognitively impaired.

I can tell you that taking Zpyrexa for 6 months, was like a pipe being shoved into my brian, and I could almost feel physically, or actually not even almost, I could feel in my body how something was just being drained from it, and now reading about Tardive Psychosis, and putting it together with anhedonia, I think what I felt pouring out of my body since something snapped inside my normal brain circuitry was dopamine.

So now I take Rhodiola Rosea since I read about it on wikipedia's entry, and the next thing I wanna try is ondansetron, which is up to my doc.

I'm 100% I will actually be more or less bed ridden for the rest of my life from this state. There's not much to do when you're noxious, don't experience pleasure, and are cognitively impaired.

And it's been 8-9 months and feels very permanent.

On a related note: Anyone knows if there is a way to measure dopamine levels in brain?

I need to make the case to doc's I have tardive psychosis caused by depleted dopamine.

It would make the world of a difference to have concrete evidence and not have to sound like a crazy in front of the healthcare but to get actual help and respect for my current condition.

I read PET scans may exist to this end but am doubtful wasting money on mentally ill people with PET's is a very probable outcome to aid me get the proper understanding from healthcare...

-- Sat Sep 21, 2013 9:49 pm --

And if they don't buy my version, and I say the word psychosis, with my medical history they will drug me to kingdom come, and a condition that is iatrogenic may worsen to a point where I don't even know how continuing life would be possible.

The help I need is respect for my condition and also possible medical help like ondansetron, but they will be very inclined to force me on antipsychotics if I say how paranoid and incapacitated I am.

To quote Wikipedia on tardive dysphrenia:

"However, these solutions [anti psychotics] carry the risk of worsening or perpetuating the iatrogenesis in the long term."

Which would also go for Tardive psychosis as, (wikipedia):

"[tardive psychosis is] induced by the use of current (dopaminergic) antipsychotics"

My life is already ruined in every sense of the word, I don't have motivation, I don't experience pleasure from any task, I'm sensitive to sound and light, and with further anti psychotics I may not even be able to hang on to whatever dull and zombie-like life is left.

Hi there, I just happened upon this posting, how u getting on with the dopamine issue? I have only experienced dopamine depletion for a short period of time after non-psychiatric drugs, but I can imagine a bit what it feels like-not pretty.

I found a supplement named dopa mucuna really helps. They give it to parkinson patients who also suffer from low dopamine. You can buy it online.

Take care with dosage when youre also taking rhodiola because too much dopa can end up pushing you into hypomania (I had this once after doubling my dose but it only lasted a few hours)

Best, tribe

It's pretty bad atm.

My main fear here is that there is literally no way out, because if I have

permanent dopamine depletion that is caused by dopaminergic AP's, I will get worse from them

and I am in a terrible state, of restlessness, inability to sleep etc.

I tried going on abilify and now after stopping them (I was in a constant semi-high state)

I'm even more restless and my baseline state is worse.

Either I'm worse now because of abilify withdrawal, or because I actually have TP and the

iatrogenesis is worsened by this class of meds. I fear the latter cause it just feels that way inside, doesn't feel like getting back on abilify will raise me to a constant level of decent life.

This is my state, before,during and after last abilify attempt:

vvvvvvvvv--------------------
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vvvvvvvvvvvvvvvvvvvvvvvvv ------------------

I'm now gonna try just using a mood stabilizer, anti depressant, rhodiola, and dopamine supplement.

If the abilify state can be a permanent sedated high where I just lay in bed and am drugged and not restless, sure that would be better.

Being this restless, insecure, unsafe, is not human. Sleep is impossible, nightmares, I wear hearing protection constantly.

Either I am worse because withdrawal or permanent further damage.

If I get back on abilify and my state goes like this:

-----------
vvvvvvvvv------
vvvvvvvvvvvvv ---
vvvvvvvvvvvvvvvv--
vvvvvvvvvvvvvvvvv -
vvvvvvvvvvvvvvvvvvv ---------------------------------

There is no going back.

I canot describe how hellish even the sedated abilify high is.

Ok I'm back on abilify. Hope I can find a decent existance and not get worse...

Maybe there's a baseline state where physiological dopamine doesn't go lower, and abilify can still help me.

Hope so.