Welbutrin

I started on 150 mg. of Welbutrin a few weeks ago. I stopped because my spouse said I was irritable. If I took a higher does, would the irritability go away? Or make it worse. Has anyone else had this problem?

jmg wrote:I started on 150 mg. of Welbutrin a few weeks ago. I stopped because my spouse said I was irritable. If I took a higher does, would the irritability go away? Or make it worse. Has anyone else had this problem?

I take 300 mg. No irritability for me. But then again, it can affect each individual quite differently. Have you read up on the leaflet if that is one of the side effects. Still, it can still affect you in different ways, no matter what and you definitely need to let you know your doctor about this. I had taken a drug that made me so sleepy that I needed to stop taking it that day and he put me on a different one that same day too. Keep your pdoc updated and they will do their very best to take care of you.

Also, it's a trial and error thing with trying new meds. You may see a change in symptoms a long time after taking the drug, or you may not. It may be due to the med, or it may not. I would have to personally talk to my pdoc before stopping it just because they may have some special instructions on that. For example, I had one drug, (don't remember the name) that I needed to wean myself from it gradually. That was the safe way to stop taking it as per doctor's orders. Wellbutrin is great for me. No weight gain, no side effects. I am very happy with it, but that's just my very own experience with it. Good luck and let us know how it goes either here on this thread or make a new one.

Are you on anything else? Taking an antidepressant with bipolar disorder without a mood stabilizer or antipsychotic can cause (hypo)mania, which can cause irritability. If that's the case, taking a higher dose would probably worsen the irritability. However, depression can also cause irritability so a higher dose might help (or might make it worse if Wellbutrin is not the med for you). Do you know if at the time you experienced other symptoms of hypomania or depression? If you don't, maybe your spouse has?
It is best to keep your pdoc in the know with these things so he or she can help you figure these things out and steer you in a good direction and prescribe the right meds.

jmg wrote:I started on 150 mg. of Welbutrin a few weeks ago. I stopped because my spouse said I was irritable. If I took a higher does, would the irritability go away? Or make it worse. Has anyone else had this problem?

I've gone on it a couple of times and it makes me irritable as hell (which also made me have to discontinue taking it).

I don't know if it goes away for others that experience this reaction, but I believe I was at 300mg before discontinuing the first time.
Years later, when I tried it again, I discontinued at 150mg for the same reason.

For me personally, Lamictal (Lamotrigine) with Cipralex (Escitalopram) are the only things I know of that have any positive impact on my depression.

It didn't make me irritable. It didn't do anything besides make me hallucinate.