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Substance Abuse Disorder

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Substance Abuse Disorder

Postby easiersaidthandone » Mon Oct 28, 2019 7:29 pm

What's the info out there on people who are more likely to overindulge in drugs? What's different in their brains?
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Re: Substance Abuse Disorder

Postby salles » Mon Oct 28, 2019 7:49 pm

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Re: Substance Abuse Disorder

Postby IDeerInHeadlightsI » Mon Oct 28, 2019 7:51 pm

Welcome back
THE DAY AFTER MONDAY WHEN MY SEROTONIN IS DEPLETED
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Re: Substance Abuse Disorder

Postby dobiedobiedoo » Mon Oct 28, 2019 8:57 pm

Both people with BPD / ASPD are prone to substance abuse. Cluster B in general is the one that the literature has most related to substance use.
Approximately 90% of individuals diagnosed with ASPD also have a co‐occurring substance use disorder. Combined with alcoholism some of them may show prefrontal brain deficits in tests.
With psychopaths it's an hyper-reactive dopamine reward that usually drives them towards substance abuse, violent behavior, etc with pwASPD substance abuse is actually linked to Impulsivity and Negative Emotionality which refers to individual differences in the propensity to experience and react with negative emotions.
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Re: Substance Abuse Disorder

Postby easiersaidthandone » Tue Oct 29, 2019 12:11 am

dobiedobiedoo wrote:it's an hyper-reactive dopamine reward


Any info on this? And how does it differ from impulsivity?
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Re: Substance Abuse Disorder

Postby dobiedobiedoo » Tue Oct 29, 2019 9:16 am

easiersaidthandone wrote:
dobiedobiedoo wrote:it's an hyper-reactive dopamine reward


Any info on this? And how does it differ from impulsivity?


Sure, some studies have found differences in the chemical activity in psychopath's brain compared to control groups. For example, they've found an increase in the release of dopamine neurotransmitter after using drugs like amphetamine, they also found an increased activity in the same region when they expected financial reward. There was also a positive correlation between the severity of Psychopathy and the activity in those regions, which may indicate that Psychopaths are more motivated to perform acts that will activate the reward system in the brain.

https://www.ncbi.nlm.nih.gov/pubmed/20228805

I suppose it's not much different from "regular" Impulsivity, but with Psychopaths this heightened responses to an anticipated rewards may at the expense of others, and despite the negative consequences of their actions.
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